Santillane is on the National Register of Historic Places. A Marker on US 220 calls it one of Botetourt County's distinguished properties. The Greek Revival house sits on a track of land originally owned by Col. George Hancock. In 1808 Hancock's daughter, Judith, married explorer William Clark at Santillane.
Travel back in time to experience the Antebellum south at the one-time home of natinal hero and pioneer, William Clark. Santillane, listed in the National Historic Registry, epitomizes southern hospitality and gracious living with its spaciousness, high ceilings and graceful wide columns. The 200 year-old manor, is now ready to accommodate your next special occasion. Twenty-three acres with mountain views and lovely gardens that include reflecting ponds, provide the backdrop for your event. Nestled in the breathtaking Blue Ridge Mountains of Virginia, Santillane offers elegant country ambiance available for weddings, rehearsal dinners, bridal showers, anniversary celebrations, family reunions, strategic planning sessions, corporate parties and retreats.