Clarke County is in the Shenandoah Valley region and its area includes the scenic Blue Ridge Mountains and the picturesque Shenandoah River. It is home to wineries, orchards, horse farms, and the State Arboretum, a 172 acre preserve at Blandy Experimental Farm that features over 5000 woody trees and shrubs from around the world and hosts numerous programs and events throughout the year, including its Arborfest and Garden Fair.

Other recreational assets to Clarke County include its access to the Appalachian Trail. The Trail is a 7.3 mile loop that begins in Snickers Gap and ends at the Blackburn Trail Center. The trail is primarily used for hiking and trail running and is accessible year-round.

The Shenandoah River follows lazily along the foot of the Blue Ridge Mountains and provides both great scenic views and an up close experience with nature. Kayaking, canoeing, tubing, fishing and camping are all part of the experience and can be rented at Watermelon Park. A public boat landing is also accessible.

Clarke County is also home to several agri-tourism farms that are popular destinations for apple and pumpkin picking, hay rides, and experiencing the beautiful fall foliage.